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ADVANCE PUBLICATIONS

Hematuria in aging men with hemophilia: Association with factor prophylaxis

Qvigstad C, Tait RC, de Moerloose P, Holme PA; ADVANCE Working Group. Res Pract Thromb Haemost. 2020;4:309–317.
Link to Wiley Online Library

 

The elevated prevalence of risk factors for chronic liver disease among ageing people with hemophilia and implications for treatment

Qvigstad C, Tait RC, Rauchensteiner S, Berntorp E, de Moerloose P, Schutgens RE, Holme PA; ADVANCE Working Group. The elevated prevalence of risk factors for chronic liver disease among ageing people with hemophilia and implications for treatment. Medicine (Baltimore). 2018 Sep;97(39):e12551. doi: 10.1097/MD.0000000000012551. PubMed PMID: 30278553; PubMed Central PMCID: PMC6181599.
Link to PubMed

 

Cardiovascular Disease in Elderly People with Haemophilia Compared with the General Population

Berger K, Schopohl D, Lowe G, Holme PA, Tait RC, Combescure C, et al. How to compare cardiovascular disease and risk factors in elderly patients with haemophilia with the general population. Haemophilia 2016;22(5):e406-16.
Link to PubMed

 

Haematuria and Hypertension in Haemophilia - A Cross-Sectional Study in Europe

Holme PA, Combescure C, Tait RC, Berntorp E, de Moerloose P; ADVANCE Working Group. Hypertension, haematuria and renal functioning in haemophilia – a cross-sectional study in Europe. Haemophilia 2016;22(2):248–255.
Link to PubMed

 

Towards a Consensus View on Managing Atrial Fibrillation in People with Haemophilia

Schutgens RE, Klamroth R, Pabinger I, Dolan G; ADVANCE Working Group. Management of atrial fibrillation in people with haemophilia - a consensus view by the ADVANCE Working Group. Haemophilia 2014;20(6):e417-420.
Link to PubMed

 

Atrial Fibrillation in Patients with Haemophilia: A Cross-Sectional Evaluation in Europe

Schutgens RE, Klamroth R, Pabinger I, Malerba M, Dolan G; ADVANCE Working Group. Atrial fibrillation in patients with haemophilia: a cross-sectional evaluation in Europe. Haemophilia 2014;20(5):682-686.
Link to PubMed

 

Clinical Management of Older People with Haemophilia

Hermans C, de Moerloose P, Dolan G; ADVANCE Working Group. Clinical management of older persons with haemophilia. Critical Reviews in Oncology/Hematology 2014;89(2):197-206.
Link to PubMed

 

Acute Coronary Syndromes

Staritz P, de Moerloose P, Schutgens R, Dolan G; ADVANCE Working Group. Applicability of the European Society of Cardiology guidelines on management of acute coronary syndromes to people with haemophilia - an assessment by the ADVANCE Working Group. Haemophilia 2013;19(6):833-840.
Link to PubMed

Additional publications on age-related topics in haemophilia

    Mannucci PM. Aging with Hemophilia: The Challenge of Appropriate Drug Prescription. Mediterr J Hematol Infect Dis. 2019 Sep 1;11(1):e2019056. doi: 10.4084/MJHID.2019.056. eCollection 2019. Review. PubMed PMID: 31528322; PubMed Central PMCID: PMC6736229.
    Link to PubMed

     

    Moreno MM, Cuesta-Barriuso R. A history of prophylaxis in haemophilia. Blood Coagul Fibrinolysis. 2019 Sep;30(1S Suppl 1):S1-S3. doi: 10.1097/MBC.0000000000000844.
    Link to PubMed

     

    Nagao A, Suzuki N, Takedani H, Yamasaki N, Chikasawa Y, Sawada A, Kanematsu T, Nojima M, Higasa S, Amano K, Fukutake K, Fujii T, Matsushita T, Suzuki T. Ischaemic events are rare, and the prevalence of hypertension is not high in Japanese adults with haemophilia: First multicentre study in Asia. Haemophilia. 2019 Jul;25(4):e223-e230. doi: 10.1111/hae.13749. Epub 2019 May 2. PubMed PMID: 31045306.
    Link to PubMed

     

    Shapiro S, Makris M. Haemophilia and ageing. Br J Haematol. 2019 Mar;184(5):712-720. doi: 10.1111/bjh.15745. Epub 2018 Dec 28. Review. PubMed PMID: 30592034.
    Link to PubMed

     

    Yang M, Sun HL, Jackson SC. Erectile dysfunction in patients with haemophilia. Haemophilia. 2019 Mar;25(2):283-288. doi: 10.1111/hae.13707. Epub 2019 Feb 28.
    Link to PubMed

     

    Zhou JY, Barnes RFW, Foster G, Iorio A, Cramer TJ, von Drygalski A. Joint Bleeding Tendencies in Adult Patients With Hemophilia: It's Not All Pharmacokinetics. Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619862052. doi: 10.1177/1076029619862052. PubMed PMID: 31298044; PubMed Central PMCID: PMC6714908.
    Link to PubMed

     

    Benson G, Auerswald G, Dolan G, Duffy A, Hermans C, Ljung R, Morfini M, Šalek Diagnosis and care of patients with mild haemophilia: practical recommendations for clinical management. Blood Transfus. 2018 Nov;16(6):535-544.  doi: 10.2450/2017.0150-17. Epub 2017 Nov 14. Review. PubMed PMID: 29328905; PubMed Central PMCID: PMC6214819.
    Link to PubMed

     

    Boccalandro E, Mancuso ME, Riva S, Pisaniello DM, Ronchetti F, Santagostino E, Peyvandi F, Solimeno LP, Mannucci PM, Pasta G. Ageing successfully with haemophilia: A multidisciplinary programme. Haemophilia. 2018 Jan;24(1):57-62. doi: 10.1111/hae.13308. Epub 2017 Aug 6.
    Link to PubMed

     

    Hirose J, Takedani H, Nojima M, Koibuchi T. Risk factors for postoperative complications of orthopedic surgery in patients with hemophilia: Second report. J Orthop. 2018 May 7;15(2):558-562. doi: 10.1016/j.jor.2018.05.039. eCollection 2018 Jun.
    Link to PubMed

     

    Husseinzadeh H, Chiasakul T, Gimotty PA, Pukenas B, Wolf R, Kelty M, Chiang E, Fogarty PF, Cuker A. Prevalence of and risk factors for cerebral microbleeds among adult patients with haemophilia A or B. Haemophilia. 2018 Mar;24(2):271-277. doi: 10.1111/hae.13398. Epub 2017 Dec 28.
    Link to PubMed

     

    Kempton CL, Buckner TW, Fridman M, Iyer NN, Cooper DL. Factors associated with pain severity, pain interference, and perception of functional abilities independent of joint status in US adults with hemophilia: Multivariable analysis of the Pain, Functional Impairment, and Quality of Life (P-FiQ) study. Eur J Haematol. 2018 Apr;100 Suppl 1:25-33. doi: 10.1111/ejh.13025.
    Link to PubMed

     

    Kiam GWP. Acquired Hemophilia in a Patient Presenting with Swollen Left Limb. Korean J Fam Med. 2019 Mar;40(2):129-132. doi: 10.4082/kjfm.17.0126. Epub 2018 Jul 13. PubMed PMID: 30001614; PubMed Central PMCID: PMC6444084.
    Link to PubMed

     

    Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A. Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls. Haemophilia. 2018 Sep;24(5):726-732. doi: 10.1111/hae.13595. Epub 2018 Aug 16. PubMed PMID: 30112863.
    Link to PubMed

     

    Marchesini E, Oliovecchio E, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Iorio A, Mannucci PM. Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population. Haemophilia. 2018 Jan;24(1):e6-e10. doi: 10.1111/hae.13379. Epub 2017 Dec 22.
    Link to PubMed

     

    Murray NP, Muñoz L, Minzer S, Lopez MA. Management of Thrombosis Risk in a Carrier of Hemophilia A with Low Factor VIII Levels with Atrial Fibrillation: A Clinical Case and Literature Review. Case Rep Hematol. 2018 Sep 5;2018:2615838. doi: 10.1155/2018/2615838. eCollection 2018. PubMed PMID: 30254772; PubMed Central PMCID: PMC6145163.
    Link to PubMed

     

    Riva S, Mancuso ME, Cortesi L, Nobili A, Santagostino E, Peyvandi F, Mannucci PM. Polypharmacy in older adults with severe haemophilia. Haemophilia. 2018 Jan;24(1):e1-e3. doi: 10.1111/hae.13262. Epub 2017 May 24.
    Link to PubMed

     

    Schnohr C, Bacher T, Andersen T, Lehrmann L, Funding E, Poulsen LH, Holm KB, Bjorner JB. Joint Mobility and Physical Function of Danish Hemophilia Patients: A Three-Wave Panel Study Spanning 24 Years. Acta Haematol. 2018;140(4):240-246. doi: 10.1159/000493783. Epub 2018 Nov 8.
    Link to PubMed

     

    Sood SL, Cheng D, Ragni M, Kessler CM, Quon D, Shapiro AD, Key NS, Manco-Johnson MJ, Cuker A, Kempton C, Wang TF, Eyster ME, Kuriakose P, von Drygalski A, Gill JC, Wheeler A, Kouides P, Escobar MA, Leissinger C, Galdzicka S, Corson M, Watson C, Konkle BA. A cross-sectional analysis of cardiovascular disease in the haemophilia population. Blood Adv. 2018 Jun 12;2(11):1325-1333. doi: 10.1182/bloodadvances.2018018226.
    Link to PubMed

     

    Boccalandro E, Mancuso ME, Riva S, Pisaniello DM, Ronchetti F, Santagostino E, Peyvandi F, Solimeno LP, Mannucci PM, Pasta G. Ageing successfully with haemophilia: A multidisciplinary programme. Haemophilia. 2018 Jan;24(1):57-62. doi: 10.1111/hae.13308. Epub 2017 Aug 6. PubMed PMID: 28780767.
    Link to PubMed

     

    Franchini M, Mannucci PM. Management of Hemophilia in Older Patients. Drugs Aging. 2017 Dec;34(12):881-889. doi: 10.1007/s40266-017-0500-8.
    Link to PubMed

     

    Giangrande PLF, Peyvandi F, O'Mahony B, Behr-Gross ME, Hilger A, Schramm W, Mannucci PM. Kreuth IV: European consensus proposals for treatment of haemophilia with coagulation factor concentrates. Haemophilia. 2017 May;23(3):370-375. doi: 10.1111/hae.13211. Epub 2017 Apr 12. PubMed PMID: 28401658.
    Link to PubMed

     

    Kiper Unal HD, Comert Ozkan M, Atilla FD, Demirci Z, Soyer N, Yildirim Simsir I, Omur O, Capaci K, Saydam G, Sahin F. Evaluation of bone mineral density and related parameters in patients with haemophilia: a single center cross-sectional study. Am J Blood Res. 2017 Nov 1;7(5):59-66. eCollection 2017.
    Link to PubMed

     

    Mahony BO, Savini L, Hara JO, Bok A. Haemophilia care in Europe - A survey of 37 countries. Haemophilia. 2017 Jul;23(4):e259-e266. doi: 10.1111/hae.13263. Epub 2017 Jun 2. PubMed PMID: 28574215.
    Link to PubMed

     

    Ono H, Sase T, Takasuna H, Tanaka Y. Mild hemophilia A presaged by recurrent postoperative hemorrhagic complications in an elderly patient. Surg Neurol Int. 2017 Sep 6;8:205. doi: 10.4103/sni.sni_235_17. eCollection 2017.
    Link to PubMed

     

    Schäffler H, Huth A, Lamprecht G, Anders O. Vedolizumab Treatment for Ulcerative Colitis in an Elderly Multimorbid Patient with Hemophilia A. Case Rep Gastroenterol. 2017 Dec 21;11(3):774-779. doi: 10.1159/000485372. eCollection 2017 Sep-Dec.
    Link to PubMed

     

    Torres-Ortuño A, Cid-Sabatel R, Barbero J, García-Dasí M. Life experience of the adult and ageing patient with haemophilia. Practical aspects for psychological support. Vox Sang. 2017 May;112(4):301-309. doi: 10.1111/vox.12501. Epub 2017 Mar 15. Review. PubMed PMID: 28299792.
    Link to PubMed

     

    Mannucci PM, Iacobelli M. Progress in the contemporary management of hemophilia: The new issue of patient aging. Eur J Intern Med 2017;43:16-21.
    Link to PubMed

     

    Schutgens REG, Voskuil M, Mauser-Bunschoten EP. Management of cardiovascular disease in aging persons with haemophilia. Hamostaseologie 2017;37(3):196-201.
    Link to PubMed

     

    Boccalandro E, Mancuso ME, Riva S, Pisaniello DM, Ronchetti F, Santagostino E, et al. Ageing successfully with haemophilia: A multidisciplinary programme. Haemophilia 2017;00:1-6.
    Link to PubMed

     

    Miesbach W, Reitter-Pfoertner SE, Klamroth R, Langer F, Wolf HH, Tiede A, et al. Co-morbidities and bleeding in elderly patients with haemophilia-A survey of the German, Austrian and Swiss Society of Thrombosis and Haemostasis Research (GTH). Haemophilia 2017;23(5):721-7.
    Link to PubMed

     

    Seaman CD, Ragni MV. The Association of Aging With Von Willebrand Factor Levels and Bleeding Risk in Type 1 Von Willebrand Disease. Clin Appl Thromb Hemost 2017;1076029617724232.
    Link to PubMed

     

    Barnes RF, Cramer TJ, Sait AS, Kruse-Jarres R, Quon DV, von Drygalski A. The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study. Int J Hypertens 2016; 2016:2014201.
    Link to PubMed

     

    Wang JD. Comorbidities of cardiovascular disease and cancer in hemophilia patients. Thromb J 2016;14(Suppl 1):34.
    Link to PubMed

     

    Eyster ME, Kong L, Li M, Schreibman IR. Long term survival in persons with hemophilia and chronic hepatitis C: 40 year outcomes of a large single center cohort. Am J Hematol 2016;91(9):e335-40.
    Link to PubMed

     

    Hollingdrake O, Mutch A, Zeissink B, Lawler SP, David M, Fitzgerald L. Haemophilia and age-related comorbidities: do men with haemophilia consult a general practitioner for men's preventative health checks? Haemophilia 2016;22(4):e335-7.
    Link to PubMed

     

    Mazepa MA, Monahan PE, Baker JR, Riske BK, Soucie JM; US Hemophilia Treatment Center Network. Men with severe hemophilia in the United States: birth cohort analysis of a large national database. Blood 2016;127(24):3073-81.
    Link to PubMed

     

    Humphries TJ, Ma A, Kessler CM, Kamalakar R, Pocoski J. A second retrospective database analysis confirms prior findings of apparent increased cardiovascular comorbidities in hemophilia A in the United States. Am J Hematol 2016;91(5):E298-9.
    Link to PubMed

     

    Sousos N, Gavriilaki E, Vakalopoulou S, Garipidou V. Understanding cardiovascular risk in hemophilia: A step towards prevention and management. Thromb Res 2016;140:14-21.
    Link to PubMed

     

    Angelini D, Konkle BA, Sood SL. Aging among persons with hemophilia: contemporary concerns. Semin Hematol 2016;53(1):35-9.
    Link to PubMed

     

    Angelini D, Sood SL. Managing older patients with hemophilia. Hematology Am Soc Hematol Educ Program 2015;2015:41-7.
    Link to PubMed

     

    Forsyth AL, Witkop M, Lambing A, Garrido C, Dunn S, Cooper DL, et al. Associations of quality of life, pain, and self-reported arthritis with age, employment, bleed rate, and utilization of hemophilia treatment center and health care provider services: results in adults with hemophilia in the HERO study. Patient Prefer Adherence 2015;9:1549-60.
    Link to PubMed

     

    Fogarty PF, Mancuso ME, Kasthuri R, Bidlingmaier C, Chitlur M, Gomez K, et al. Presentation and management of acute coronary syndromes among adult persons with haemophilia: results of an international, retrospective, 10-year survey. Haemophilia 2015;21(5):589-97.
    Link to PubMed

     

    Riva S, Nobili A, Djade CD, Mancuso ME, Santagostino E, Pravettoni G. Cognitive and psychological profiles in treatment compliance: a study in an elderly population with hemophilia. Clin Interv Aging 2015;10:1141-6.
    Link to PubMed

     

    Manners PJ, Price P, Buurman D, Lewin B, Smith B, Cole CH. Joint Aspiration for Acute Hemarthrosis in Children Receiving Factor VIII Prophylaxis for Severe Hemophilia: 11-year Safety Data. The Journal of Rheumatology 2015;42(5):885-90.
    Link to PubMed

     

    Huang YC, Tsan YT, Chan WC, Wang JD, Chu WM, Fu YC, et al. Incidence and survival of cancers among 1,054 hemophilia patients: A nationwide and 14-year cohort study. American Journal of Hematology 2015;90(4):E55-9.
    Link to PubMed

     

    Canaro M, Goranova-Marinova V, Berntorp E. The ageing patient with haemophilia. Eur J Haematol 2015;94 Suppl 77:17-22.
    Link to PubMed

     

    Jackson SC, Yang M, Minuk L, Sholzberg M, St-Louis J, Iorio A, et al. Prophylaxis in older Canadian adults with hemophilia A: lessons and more questions. BMC Hematology 2015;15:4.
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    Perez Botero J, Spoon DB, Patnaik MS, Ashrani AA, Trousdale RT, Pruthi RK. Incidence of symptomatic venous thromboembolism in patients with hemophilia undergoing joint replacement surgery: a retrospective study. Thrombosis Research 2015;135(1):109-13.
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    Zaliuniene R, Aleksejuniene J, Peciuliene V, Brukiene V. Dental health and disease in patients with haemophilia--a case-control study. Haemophilia 2014;20(3):e194-8.
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    Sait AS, Kuo A, Bettencourt R, Bergstrom J, Allison M, von Drygalski A. Risk assessment for coronary heart disease in patients with haemophilia: a single centre study in the United States. Haemophilia 2014;20(6):763-70.
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    Liu CJ, Yu YB, Teng CJ, Hung YP, Hu YW, Hong YC, et al. Increased cancer risk in patients with haemophilia A: a nationwide population-based 14-year study in Taiwan. Haemophilia 2014;20(6):741-6.
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    Zanon E, Manara R, Milan M, Brandolin B, Mapelli D, Mardari R, et al. Cognitive dysfunctions and cerebral microbleeds in adult patients with haemophilia A: a clinical and MRI pilot-study. Thrombosis Research 2014;134(4):851-5.
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    Pocoski J, Ma A, Kessler CM, Boklage S, Humphries TJ. Cardiovascular comorbidities are increased in U.S. patients with haemophilia A: a retrospective database analysis. Haemophilia 2014;20(4):472-8.
    Link to PubMed

     

    Zaliuniene R, Peciuliene V, Brukiene V, Aleksejuniene J. Hemophilia and oral health. Stomatologija 2014;16(4):127-31.
    Link to PubMed

     

    Kulkarni R, Mauser-Bunschoten EP, Stedman C, Street A. Medical co-morbidities and practice. Haemophilia 2014;20 Suppl 4:130-6.
    Link to PubMed

     

    Coppola A, Morfini M, Cimino E, Tufano A, Cerbone AM, Di Minno G. Current and evolving features in the clinical management of haemophilia. Blood Transfus 2014;12 Suppl 3:s554-62.
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    Calizzani G, Menichini I, Candura F, Lanzoni M, Profili S, Tamburrini MR, et al. Definition of an organisational model for the prevention and reduction of health and social impacts of inherited bleeding disorders. Blood Transfus 2014;12 Suppl 3:s582-8.
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    Göhler S, Stäuber F, Brunner A, Czepa D, Krüger S, Wendel M, et al. [Age-related activation of the muscles during upright standing in patients with haemophilia]. Hamostaseologie 2014;34 Suppl 1:S36-42. German.
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    Aznar JA, Garcia-Dasi M, Perez-Alenda S, Marco A, Jaca M, Moret A, et al. Secondary prophylaxis vs. on-demand treatment to improve quality of life in severe adult haemophilia A patients: a prospective study in a single centre. Vox Sanguinis 2014;106(1):68-74.
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    Report on the Annual Global Survey 2013.
    Link to PubMed

     

    Schramm W, Rieger A. Morbidity and mortality of haemophilia patients in Germany. Survey results 2011/2012. Hamostaseologie 2013;33 Suppl 1:S5-9.
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    Miesbach W, Schelle G, Kalnins W. [Life with haemophilia. The patient's perspective of ageing]. Hamostaseologie 2013;33 Suppl 1:S22-4. German.
    Link to PubMed

     

    Di Minno MD, Ambrosino P, Franchini M, Coppola A, Di Minno G. Arthropathy in patients with moderate hemophilia A: A systematic review of the literature. Seminars in Thrombosis and Hemostasis 2013;39(7):723-31.
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    Girolami A, Berti de Marinis G, Bertozzi I, Peroni E, Tasinato V, Lombardi AM. Discrepant ratios of arterial vs. venous thrombosis in hemophilias A and B as compared to FVII deficiency. European Journal of Haematology 2013;91(2):152-6.
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    von Drygalski A, Kolaitis NA, Bettencourt R, Bergstrom J, Kruse-Jarres R, Quon DV, et al. Prevalence and risk factors for hypertension in hemophilia. Hypertension 2013;62(1):209-15.
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    Lovdahl S, Henriksson KM, Baghaei F, Holmstrom M, Nilsson JA, Berntorp E, et al. Incidence, mortality rates and causes of deaths in haemophilia patients in Sweden. Haemophilia 2013;19(3):362-9.
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    Srivastava A, Brewer AK, Mauser-Bunschoten EP, Key NS, Kitchen S, Llinas A,et al. Guidelines for the management of hemophilia. Haemophilia 2013;19(1):e1-47.
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    Fransen van de Putte DE, Fischer K, Makris M, Tait RC, Chowdary P, Collins PW, et al. Unfavourable cardiovascular disease risk profiles in a cohort of Dutch and British haemophilia patients. Thrombosis and Haemostasis 2013;109(1):16-23.
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    Baker JR, Riske B, Drake JH, Forsberg AD, Atwood R, Voutsis M, et al. US Hemophilia Treatment Center population trends 1990-2010: patient diagnoses, demographics, health services utilization. Haemophilia 2013;19(1):21-6.
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    Ghosh K, Shetty S. Bone health in persons with haemophilia: a review. European Journal of Haematology 2012;89(2):95-102.
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    Dunn AL, Austin H, Soucie JM. Prevalence of malignancies among U.S. male patients with haemophilia: a review of the Haemophilia Surveillance System. Haemophilia 2012;18(4):532-9.
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    Witkop M, Lambing A, Divine G, Kachalsky E, Rushlow D, Dinnen J. A national study of pain in the bleeding disorders community: a description of haemophilia pain. Haemophilia 2012;18(3):e115-9.
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    Coppola A, Franchini M, Makris M, Santagostino E, Di Minno G, Mannucci PM. Thrombotic adverse events to coagulation factor concentrates for treatment of patients with haemophilia and von Willebrand disease: a systematic review of prospective studies. Haemophilia 2012;18(3):e173-87.
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    Zwiers M, Lefrandt JD, Mulder DJ, Smit AJ, Gans RO, Vliegenthart R, et al. Coronary artery calcification score and carotid intima-media thickness in patients with hemophilia. Journal of Thrombosis and Haemostasis 2012;10(1):23-9.
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    Tagliaferri A, Di Perna C, Santoro C, Schinco P, Santoro R, Rossetti G, et al. Cancers in patients with hemophilia: a retrospective study from the Italian Association of Hemophilia Centers. Journal of Thrombosis and Haemostasis 2012;10(1):90-5.
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    Meijer K, Haagsma EB. HCV-related liver cancer in people with haemophilia. Haemophilia 2012;18(1):17-24.
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    Biere-Rafi S, Tuinenburg A, Haak BW, Peters M, Huijgen R, De Groot E, et al. Factor VIII deficiency does not protect against atherosclerosis. Journal of Thrombosis and Haemostasis 2012;10(1):30-7.
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    Ragni MV, Moore CG. Atherosclerotic heart disease: prevalence and risk factors in hospitalized men with haemophilia A. Haemophilia 2011;17(6):867-71.
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    Sharathkumar AA, Soucie JM, Trawinski B, Greist A, Shapiro AD. Prevalence and risk factors of cardiovascular disease (CVD) events among patients with haemophilia: experience of a single haemophilia treatment centre in the United States (US). Haemophilia 2011;17(4):597-604.
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    Khleif AA, Rodriguez N, Brown D, Escobar MA. Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care. Journal of Aging Research 2011;2011:985703.
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    Biere-Rafi S, Baarslag MA, Peters M, Kruip MJ, Kraaijenhagen RA, Den Heijer M, et al. Cardiovascular risk assessment in haemophilia patients. Thrombosis and Haemostasis 2011;105(2):274-8.
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    Ragni MV, Moore CG, Soadwa K, Nalesnik MA, Zajko AB, Cortese-Hassett A, et al. Impact of HIV on liver fibrosis in men with hepatitis C infection and haemophilia. Haemophilia 2011;17(1):103-11.
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    Miesbach W, Seifried E. Does haemophilia influence cancer-related mortality in HIV-negative patients? Haemophilia 2011;17(1):55-60.
    Link to PubMed

     

    Dolan G. The challenge of an ageing haemophilic population. Haemophilia 2010;16 Suppl 5:11-6.
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    Tagliaferri A, Rivolta GF, Iorio A, Oliovecchio E, Mancuso ME, Morfini M, et al. Mortality and causes of death in Italian persons with haemophilia, 1990-2007. Haemophilia 2010;16(3):437-46.
    Link to PubMed

     

    Dunn AL. Malignancy in patients with haemophilia: a review of the literature. Haemophilia 2010;16(3):427-36.
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    Iorio A, Fabbriciani G, Marcucci M, Brozzetti M, Filipponi P. Bone mineral density in haemophilia patients. A meta-analysis. Thrombosis and Haemostasis 2010;103(3):596-603.
    Link to PubMed

     

    Foley CJ, Nichols L, Jeong K, Moore CG, Ragni MV. Coronary atherosclerosis and cardiovascular mortality in hemophilia. Journal of Thrombosis and Haemostasis 2010;8(1):208-11.
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    Konkle BA, Kessler C, Aledort L, Andersen J, Fogarty P, Kouides P, et al. Emerging clinical concerns in the ageing haemophilia patient. Haemophilia 2009;15(6):1197-209.
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    Mauser-Bunschoten EP, Fransen Van De Putte DE, Schutgens RE. Co-morbidity in the ageing haemophilia patient: the down side of increased life expectancy. Haemophilia 2009;15(4):853-63.
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